Amniotic Membrane Transplantation in Ophthalmology: An Overview
The amniotic membrane (AM) is the innermost layer of the placenta, comprising a thick basement membrane and an avascular stromal matrix. It has been used in ophthalmology since the early twentieth century, with renewed interest following the work of Kim and Tseng in the 1990s, who demonstrated its efficacy in ocular surface reconstruction (1). Its unique biological properties, including anti-inflammatory, anti-fibrotic, anti- angiogenic, and pro-epithelialisation effects, make it a versatile adjunct in the management of a wide range of ocular surface conditions (1,2). Amniotic membrane transplantation (AMT) is now an established surgical technique in corneal and anterior segment practice, and familiarity with its indications and applications is essential for ophthalmic trainees.
