Retinopathy of Prematurity: An Overview and Practical Guide for Foundation Doctors

  • Reading time:6 mins read
  • Post author:Maya Keiralla
  • Post category:Article

Retinopathy of prematurity (ROP) is a disorder of abnormal retinal vascular development unique to preterm infants, and one of the leading causes of preventable childhood blindness worldwide (1,2). Foundation doctors rotating through neonatal units, paediatrics or ophthalmology will often encounter it, and an adequate understanding supports safe handover, informed conversations with parents, and recognition of when urgent ophthalmic referral is needed. This article gives a brief, practical overview of ROP's pathophysiology, screening and treatment for a foundation doctor audience.

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Recognition, Escalation and Delay in Acute Eye Care

  • Reading time:7 mins read
  • Post author:Barnaby Carr
  • Post category:Article

Roughly one in twenty-five emergency department attendances involves an ocular problem, and most of these patients are first assessed not by an ophthalmologist but by resident clinicians covering the acute take. Resident doctors are therefore well placed to detect serious eye disease, not because of specialist training but because of where they sit in the system. The argument developed here is that the limiting factor at that point of entry is rarely diagnostic knowledge. It is timescale, and whether the clinician who sees the patient first can identify the correct escalation route. The resident doctor does not need to be an ophthalmologist. They need to know which clock the patient is on, and to refer before it runs out.

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Acute anterior uveitis and its associations with systemic disease

  • Reading time:6 mins read
  • Post author:Peter Rae
  • Post category:Article

Anterior uveitis is a condition in which there is inflammation of the anterior structures of the uvea – the iris and ciliary body. The most common presentation is acute anterior uveitis (AAU), with presenting symptoms of rapid-onset pain, photophobia and red eye, which is most commonly unilateral. On slit-lamp examination, inflammatory cells must be present in the anterior chamber to diagnose AAU. There may also be flare, hypopyon, keratic precipitates and posterior synechiae.

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Eye Drops on the Drug Chart: What Every Junior Doctor Should Know

  • Reading time:9 mins read
  • Post author:Mandeep Brar
  • Post category:Article

A patient on the ward with heart block is prescribed timolol eye drops. Another patient taking oral acetazolamide develops paraesthesia and is found to have worsening renal function. Later that week, you are asked to prescribe antibiotic drops for a red eye. How confident are you that you know what to prescribe – and what to look out for?

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Klebsiella pneumoniae Keratitis Following Hematopoietic Stem Cell Transplantation in a Patient with Lymphoma

  • Reading time:9 mins read
  • Post author:Junqi Liang, Zijun Zhang, Ahyan Ilman Qudsi
  • Post category:Article

Klebsiella pneumoniae keratitis is uncommon but may progress rapidly in immunocompromised patients, leading to severe corneal destruction. We report a 42-year-old man with a history of lymphoma, hematopoietic stem cell transplantation, and chronic graft-versus-host disease who developed progressive keratitis after previous corneal ulcer repair. On presentation, visual acuity in the affected eye was hand motions, with a deep corneal ulcer, proliferative lesion, and peripheral neovascularization. Corneal culture grew K. pneumoniae. Despite intensive antimicrobial therapy, the patient required penetrating keratoplasty, anterior chamber reconstruction, and subsequent corneal repair procedures. The infection was ultimately controlled. This case highlights the increased risk of aggressive infectious keratitis in patients with post-transplant immune dysfunction and chronic ocular surface disease, and underscores the importance of early microbiological diagnosis, targeted antimicrobial therapy, and timely surgical intervention.

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