The European Vitreoretinal Society (EVRS) Meeting 2024, held in the breathtaking city of Budapest, Hungary, in November 2024, was a remarkable convergence of knowledge, innovation, and collaboration in the field of vitreoretinal medicine. Renowned for its commitment to advancing retinal care, the EVRS once again provided an exceptional platform for sharing groundbreaking research, discussing complex cases, and exploring the future of ophthalmology.

Migraines are a common presentation to the emergency department. They are noted to be the most common primary headache disorder and ranked the 2nd most disabling disease globally by the Global Burden of Disease study 2016. Data from the National Health Service (NHS) in the United Kingdom further support this, with admission rates for headaches having risen by 14% over a 5-year period in 2018/19.

Ahmad Khalifa Introduction My medical elective experience in Syria revealed the profound impact of the ongoing conflict and resource limitations on healthcare delivery, underscoring the need for a comprehensive understanding…

This article will discuss where we currently stand in the use of retinal Imaging methods with the aid of AI for the development of ophthalmological practice. A specific implementation of AI that is available now relies on pattern recognition and grouping of images with similar findings and patterns which can be used to aid in the research and development of a better understanding of retinal pathologies, particularly chronic ones. However, the prospective use that I want to discuss is the clinical aid of AI in early triage for use by non-ophthalmology clinicians who usually have not one but multiple barriers in providing enough information for an effective referral/handover to more senior clinicians specializing in Ophthalmology.

Uveitis is an umbrella term that refers to inflammation of the uveal tract and adjacent structures of the eye, which can be infectious or non-infectious in aetiology. Uveitis can be classified as anterior, intermediate, posterior, or panuveitis based on the anatomical location of the inflammation in the eye. Anterior uveitis is inflammation of the iris and ciliary body and is the most common form of uveitis. Intermediate uveitis is defined as inflammatory cells in the vitreous humour. Posterior uveitis is defined as inflammation of the retina/choroid (choroiditis, chorioretinitis, retinitis) and panuveitis is inflammation of all three parts of the uvea, i.e. the anterior chamber, vitreous humour, and choroid or retina.

Phototransduction is the process by which light stimuli are converted into electrical signals in the retina, enabling vision. This biochemical cascade allows photoreceptor cells—rods and cones—to detect light, initiate electrical signalling, and ultimately send this information to the brain for visual perception. Disruptions in these pathways, whether in the phototransduction process or in the recycling mechanisms, can lead to various visual disorders. Mutations in genes responsible for phototransduction and its components often result in retinal diseases, such as retinitis pigmentosa and congenital stationary night blindness. This paper will explore the phototransduction pathway, the recycling of visual pigments, and common gene mutations associated with retinal diseases.

Epiretinal membrane (ERM) may be defined as the pre-retinal proliferation of myofibroblastic cells associated with the extracellular matrix (ECM). Although various aetiologies have been documented, these cannot be distinguished through histological variations. This review elucidates the most recent evidence concerning the epidemiology, aetiology, clinical findings, and investigation of ERMs.

Trachoma is a form of keratoconjunctivitis and the leading infectious cause of blindness worldwide. This eye disease results from an infection with the bacterium Chlamydia trachomatis serotypes A-C. It continues to pose a substantial burden on global health, particularly in regions with poor sanitation, inadequate hygiene practices, and limited access to clean water and healthcare services.

Leber’s Hereditary Optic Neuropathy (LHON) is a mitochondrial disorder characterised by severe vision loss, often manifesting in young adulthood. It was first described by Theodore Leber in 1871, but the pattern of inheritance was not confirmed until 1988 by Wallace et al. It is one of the most common inherited optic neuropathies, with the hallmark being bilateral, painless central vision loss.